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Hydroxychloroquine, an antimalarial drug with a history spanning decades, recently surfaced in discussions about potential COVID-19 treatments. It’s crucial to understand its primary uses, potential side effects, and necessary precautions. Let’s delve into the intricate details of hydroxychloroquine.


Primarily, hydroxychloroquine has been a cornerstone in the prevention and treatment of malaria, a mosquito-borne infectious disease. Besides malaria, hydroxychloroquine uses also extend to treating autoimmune diseases like lupus and rheumatoid arthritis. Its anti-inflammatory properties have made it valuable in managing these conditions.


The dosage of hydroxychloroquine varies depending on the condition being treated:

For malaria prevention: Typically, adults are prescribed hydroxychloroquine 400 mg, taken once weekly. The initial dose is usually given 1-2 weeks before traveling to an area where malaria is prevalent.

For lupus and rheumatoid arthritis: Dosages can range from hydroxychloroquine 200 mg to 400 mg daily.

Always follow a physician’s prescription as the right dosage depends on various factors, including the patient’s condition, weight, and age.

Side Effects

Like all medications, hydroxychloroquine isn’t devoid of side effects. While many are mild, some can be severe. Common hydroxychloroquine side effects include:

Nausea or stomach cramps.

Dizziness or headache.


Mood changes.

More severe side effects, though rarer, include:

Vision changes or blurry vision.

Muscle weakness.

Slow heartbeat.

Hearing changes like ringing in the ears.

Severe stomach or abdominal pain.

Dark urine.

Yellowing eyes or skin (jaundice).

It’s imperative to seek immediate medical attention if you notice any severe side effects.


Given the broad range of hydroxychloroquine side effects, certain precautions are warranted:

Individuals with a history of eye diseases should undergo regular eye exams, as hydroxychloroquine can sometimes affect vision.

Those with liver or kidney diseases, alcoholism, or other health conditions should disclose this to their doctor, as it might affect how hydroxychloroquine works or is processed in the body.

The drug can cause fluctuations in blood sugar levels, so diabetic patients should monitor their levels closely.


Hydroxychloroquine can interact adversely with several medications, especially those affecting the heart, like arrhythmia drugs. Always ensure that your physician knows all the medications and supplements you’re taking.


Symptoms of hydroxychloroquine overdose include drowsiness, dizziness, seizures, or difficulty breathing. If someone is suspected of overdosing, they should get emergency help immediately.

Hydroxychloroquine and COVID

The hydroxychloroquine COVID connection garnered global attention as the drug was hypothesized as a potential treatment for the virus. However, subsequent research has provided mixed results, and in many cases, health authorities have not endorsed its widespread use for COVID-19 outside of clinical trials.

Cost and Accessibility

While the hydroxychloroquine cost can vary based on location and insurance, it’s generally affordable, especially in its generic form. With rising interest, many wonder about the availability of hydroxychloroquine over the counter. However, in most regions, a prescription is required. If you’re contemplating hydroxychloroquine for sale or purchase, consult with a healthcare professional.

In Conclusion

Hydroxychloroquine has a long history in the world of medicine. Whether you’re considering it for malaria, autoimmune conditions, or have heard about its potential ties with COVID-19, it’s essential to be informed about its uses, side effects, and precautions. Remember to consult a healthcare professional before making any decisions regarding medication.